The ionization chamber is the simplest type of gaseous ionisation detector, and is widely used for the detection and measurement of many types of ionizing radiation, including X-rays, gamma rays, and beta particles. Conventionally, the term "ionization chamber" refers exclusively to those detectors which collect all the charges created by direct ionization within the gas through the application of an electric field. It uses the discrete charges created by each interaction between the incident radiation and the gas to produce an output in the form of a small direct current. This means individual ionising events cannot be measured, so the energy of different types of radiation cannot be differentiated, but it gives a very good measurement of overall ionising effect.

It has a good uniform response to radiation over a wide range of energies and is the preferred means of measuring high levels of gamma radiation, such as in a radiation hot cell as they can tolerate prolonged periods in high radiation fields without degradation. They are widely used in the nuclear power industry, research labs, fire detection, radiation protection, and environmental monitoring.